I've been to California several times now, but never to San Francisco. And everyone keeps telling me that I'll love it, since it's like the New York City of the west coast.
I'm staying in the downtown area at the Warwick Regis, which looks really old fashioned and pretty.
While there I'm going to see Alcatraz and go to a wine tour in Sonoma, all the fun touristy stuff.
For a cool SanFran blog check out Just Another Week.